Glycoengineering
K-Dense-AI/drug-discovery-agent-skillsAnalyze and engineer protein glycosylation. Scan sequences for canonical N-glycosylation sequons (N-X-S/T with X not proline, including overlapping sites), predict O-GalNAc hotspots, read glycan notation, and reach the curated external tooling (NetNGlyc, NetOGlyc, GlycoShield, GlycoWorkbench, GlyTouCan, GlyConnect). Use this skill for therapeutic antibody glycoengineering and afucosylation for ADCC, Fc glycan control, glycan shielding in vaccine immunogen design, sequon removal or insertion, and half-life engineering through sialylation. Also trigger on N-glycosylation, sequon, NXS/NXT, O-glyc...
At a glance
This skill is for Research and helps you predict protein glycosylation sites, design antibody fc glycans, and engineer sequons for therapeutic proteins.
git clone --depth 1 https://github.com/K-Dense-AI/drug-discovery-agent-skills
cp -r drug-discovery-agent-skills/skills/glycoengineering ~/.claude/skills/glycoengineering
bioinformaticsprotein-engineeringTherapeuticsGlycobiologyAntibodiesSequon
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